All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in each cell. Mistakes or failures […]
Combining genetic risk with cardiovascular disease risk factors—such as high LDL cholesterol, obesity, and hypertension—may predict who is more likely to develop dementia, according to a new study led by UC San Francisco.This article was […]
Researchers at the University of Toronto’s Temerty Faculty of Medicine have found widespread genetic and protein changes in the brain cells of people with amyotrophic lateral sclerosis (ALS), which may help shed light on mechanisms […]
Among friends and family of those who die by suicide, a common refrain is: I didn’t know. While some people who die by suicide have prior attempts, about half of people who die by suicide […]
Researchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such as diabetes, heart disease, autoimmune […]
All starting from the same DNA, neurons ultimately take on individual characteristics in the brain and body. Differences in which genes they transcribe into RNA help determine which type of neuron they become, and from […]
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease caused by repetitive head impacts (RHI). However, individuals with similar RHI exposure have shown differing pathology, suggesting a role for genetic variation. While a common Transmembrane Protein106B […]
Researchers from The University of Texas MD Anderson Cancer Center identified a new role for heat shock protein 90 (HSP90) in cancer predisposition and treatment resistance.This article was originally published on MedicalXpress.com
Chronic wounds (CWs), like diabetic ulcers or pressure sores, are a major health care challenge, especially in the elderly. These wounds, marked by persistent inflammation, often lead to infection and poor patient outcomes. While inflammation […]
The immune system plays a crucial role in fighting tumors and metastases. Consequently, it is decisive to conduct cancer research in mouse models with an immune system that is as natural as possible—which is easier […]
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