Genetics

A new research paper titled “Knockout of AMD-associated gene POLDIP2 reduces mitochondrial superoxide in human retinal pigment epithelial cells” has been published in Aging.This article was originally published on MedicalXpress.com

With the huge abundance of genomic data generated from life science experiments, processing large datasets remains a challenge in the field of bioinformatics. During the COVID-19 pandemic, the limited capabilities of existing bioinformatics tools meant […]

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes. However, this process is associated with side effects including unwanted mutations and toxicity. Therefore, a new technology that […]

Second only to the notorious TP53 gene, the genes for assemblages known as mSWI/SNF protein complexes are the most frequently mutated entities in cancer cells. Made up of 10 to 15 subunits, the complexes are […]

University of Nevada, Las Vegas, researchers have identified a correlation between Alzheimer’s disease and specific gut microbiota populations. In a paper published in Scientific Reports titled “Genetic correlations between Alzheimer’s disease and gut microbiome genera,” […]

Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex. Mutations in the same genes can lead to different subtypes of tumors in different people. Currently, […]

Alagille syndrome, a genetic disease estimated to affect 1 in 30,000 individuals, is caused by mutations in the gene JAG1 in most cases. The mutations affect multiple organs including the liver where it often results […]

Often an incidental finding on brain scans looking for trauma or other neurological conditions, arachnoid cysts (ACs) are small, fluid-filled sacs within the arachnoid membrane, one of three layers protecting the brain and spinal cord. […]

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes. One of these types of cancer genes are […]

A study by Indiana University School of Medicine researchers sheds new light on the development and treatment of a rare form of muscular dystrophy. The study’s findings were recently published in Nature Communications.This article was […]