The genetic roots of a disease or disorder do not always grow into clear-cut, easily diagnosed clinical features. Even if a parent and child have the same genetic marker implicated in an outcome, such as […]
Scientists at City of Hope have uncovered a gene called SMOC1 that plays a surprising role in the development of type 2 diabetes (T2D) by converting pancreatic cells that normally produce insulin into those that […]
Results of a recently published long-term follow-up of the ASAP trial, which was conducted at universities and clinics across Germany, show that the genetic risk of disease, not remission status, determines overall survival of patients […]
Researchers at Texas Children’s Neurological Research Institute (NRI) and Baylor College of Medicine have developed a powerful new tool within the Genome Aggregation Database (gnomAD) to sharpen the accuracy of genetic testing—a breakthrough with direct […]
University College London’s National Amyloidosis Center leads a multinational team reporting that a single infusion of an in vivo gene-editing therapy (nexiguran ziclumeran) produced rapid, deep, and durable reductions in serum transthyretin for hereditary transthyretin […]
A new study, published in Nature Genetics, created the largest genetic map of human metabolism, revealing new insights into the role of metabolites in health and disease and creating a blueprint for further research.This article […]
Scientists have found a direct link between osteoporosis and rotator cuff tears, two conditions that often develop with age. Using health and genetic data from hundreds of thousands of people, researchers showed that fragile bones […]
A study conducted by The Hong Kong University of Science and Technology (HKUST) has demonstrated that a genetic variant, TREM2 H157Y, significantly increases the risk of Alzheimer’s disease (AD) in individuals of ethnic Chinese descent. […]
In a paper published in Nature Communications, researchers at Vanderbilt University Medical Center’s Department of Otolaryngology–Head and Neck Surgery leveraged two main studies—one focused on behavior and one focused on genetics—to highlight the correlation between […]
Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental factors, as well as existing medical conditions. Known genetic risk factors for CKD include mutations in a […]
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