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Genetics

Genetics

Unlocking the Naᵥ1.9 channel: A hidden switch in pain and itch disorders

June 3, 2025 Medical Xpress.com

Imagine not feeling any pain when you stub your toe—or, conversely, experiencing constant burning pain or itching without an obvious cause. For some people, this is reality, caused by mutations in a single protein: the […]

Genetics

Brain study identifies microRNAs that likely contribute to psychiatric and neurodegenerative disorders

June 3, 2025 Medical Xpress.com

A study in Nature Aging from researchers at the UC Davis School of Medicine has identified specific microRNAs—non-coding RNAs that regulate gene expression within cells—that likely contribute to bipolar disorder, depression, schizophrenia, post-traumatic stress disorder […]

Genetics

DNA regions and key genes that activate liver regeneration identified

June 3, 2025 Medical Xpress.com

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury or partial resection. A study led by researchers at the University of Barcelona has identified the DNA […]

Genetics

CRISPR gene editing in blood stem cells linked to premature aging effects: Study offers solutions

June 3, 2025 Medical Xpress.com

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising […]

Genetics

Why do some people need less sleep than others? A gene variation could have something to do with it

June 3, 2025 Medical Xpress.com

Have you ever noticed how some people bounce out of bed after just a few hours of sleep, while others can barely function without a solid eight hours?This article was originally published on MedicalXpress.com

Genetics

Genetic analysis reveals shared biological mechanisms in depression, bipolar disorder and schizophrenia

June 2, 2025 Medical Xpress.com

Researchers at the Max Planck Institute of Psychiatry (MPI), Helmholtz Munich and the University of Sydney have identified biological mechanisms that are shared across psychiatric disorders.This article was originally published on MedicalXpress.com

Genetics

Genome doubling emerges as key event in cancer metastasis, shaping tumor evolution

June 2, 2025 Medical Xpress.com

When cancer spreads from a primary tumor to new sites throughout the body, it undergoes changes that increase its genetic complexity.This article was originally published on MedicalXpress.com

Genetics

Understanding the genomic complexities of glioblastoma tumors

June 2, 2025 Medical Xpress.com

The genetic makeup and structure of glioblastoma tumors can shift dramatically across different regions of a single tumor, according to a Northwestern Medicine study published in Science Advances.This article was originally published on MedicalXpress.com

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Genetics

Clinical trial shows biomarkers hold clue in treating aggressive prostate cancer

June 1, 2025 Medical Xpress.com

Many men with aggressive prostate cancer can experience a high rate of recurrence despite treatment.This article was originally published on MedicalXpress.com

Genetics

Multiple genetic variants could predict who benefits from alcohol addiction drug

May 30, 2025 Medical Xpress.com

Alcohol-related genetic variants influence the effects of a medication for treating alcohol use disorder (AUD), according to an innovative study. The findings point to opportunities for new research approaches and customized treatments for patients.This article […]

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