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Genetics

Genetics

How sex-based differences shape immune responses and disease risks

August 8, 2025 Medical Xpress.com

Many diseases affect men and women differently. Asthma tends to strike men earlier in life, yet more women develop asthma as they get older. Parkinson’s is more common in men, but Alzheimer’s is more common […]

Genetics

Human eggs are protected from age-related genetic mutations, mtDNA study finds

August 7, 2025 Medical Xpress.com

As we age, the genes in our cells accumulate more mutations. This is one of the contributory factors to age-related diseases and the aging process. However, in a new study published in Science Advances, researchers […]

Genetics

Scrambled RNA nudges millions of people towards type 2 diabetes, research reveals

August 6, 2025 Medical Xpress.com

Mutations in a single gene, HNF1A, are known to cause MODY3, a rare, early-onset form of diabetes. Smaller-scale mutations in the very same gene are also common and quietly nudge millions of people toward type […]

Genetics

Kids of obese parents more likely to develop obesity due to inheriting related genes

August 5, 2025 Medical Xpress.com

A new study finds that kids with obesity are more likely to have obese parents because they inherit obesity-related genes, and to a smaller extent, are impacted indirectly by genes carried by the mother—even when […]

Genetics

Genes reveal why some older people suffer from frailty

August 5, 2025 Medical Xpress.com

A new study has identified genetic variants linked to brain function, immune defense and metabolism that contribute to the development of frailty in older people. The study, published in Nature Aging by researchers from Karolinska […]

Genetics

Lifestyle interventions reshape gene regulation in skeletal muscle of Asians

August 1, 2025 Medical Xpress.com

Researchers from the National University of Singapore (NUS) have revealed that diet and exercise can change gene regulation in the skeletal muscle of East Asians, highlighting the critical role of gene-lifestyle (G x L) interactions […]

Genetics

X-SCID gene therapy gives scientists a rare glimpse into early immune system

July 31, 2025 Medical Xpress.com

Findings from St. Jude Children’s Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life.This article was originally published on MedicalXpress.com

Genetics

Hibernator ‘superpowers’ may lie hidden in human DNA

July 31, 2025 Medical Xpress.com

Animals that hibernate are incredibly resilient. They can spend months without food or water, muscles refusing to atrophy, body temperature dropping to near freezing as their metabolism and brain activity slow to a crawl. When […]

Genetics

Research confirms role of DJ-1 gene in Parkinson’s disease

July 30, 2025 Medical Xpress.com

A mutant DJ-1 gene causes recessive Parkinson’s disease, but the molecular mechanism of this process has not been well studied. To understand how DJ-1 hydrolyzes cyclic 3-phosphoglyceric anhydride—a highly reactive, toxic cellular metabolite—researchers from Japan […]

Genetics

Study identifies genes that can predict response to immunotherapy in melanoma patients

July 30, 2025 Medical Xpress.com

Brazilian researchers have taken an important step toward precision medicine by identifying four genes that can predict which melanoma patients will not respond to immunotherapy. Although this treatment has revolutionized the fight against melanoma, the […]

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