An investigational gene therapy has successfully restored immune function in all nine children treated with the rare and life-threatening immune disorder called severe leukocyte adhesion deficiency-I, or LAD-I, in an international clinical trial co-led by […]
In recent years, there has been a growing trend of an aging patient population and an increasing prevalence of age-associated diseases, underscoring the need for advancing research into the biological mechanisms of aging. Of particular […]
Nagoya University researchers in Japan have found that drug effectiveness, alcohol tolerance, and carbohydrate metabolism change with the seasons. Their findings are based on a comprehensive seasonal gene expression map, which investigated over 54,000 genes […]
Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer’s, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein shortage primarily affects the brain’s blood vessels.This article was originally published […]
Height is determined by thousands of signals in our genes. Three world experts on human growth, including Associate Professor Louise Bicknell from Otago’s Department of Biochemistry, have undertaken a significant review summarizing published research into […]
One in three Americans is likely to be affected by a brain disorder in their lifetime. Many of these conditions, such as Alzheimer’s disease or severe developmental disorders, have no reliable treatment.This article was originally […]
Found in the Finnish population, a rare variant of the TYROBP gene significantly increases the risk of Alzheimer’s disease, a new study led by the University of Eastern Finland shows. This gene variant affects the […]
The U.S. Food and Drug Administration has approved Abeona Therapeutics’ Zevaskyn (prademagene zamikeracel) for patients with the rare, genetic skin disorder recessive dystrophic epidermolysis bullosa.This article was originally published on MedicalXpress.com
Some proteins in human cells that are implicated in cancer also have causal roles in neurodevelopmental disorders, raising the possibility of repurposing targeted cancer therapies to help address neurodevelopmental diseases.This article was originally published on […]
Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. While scientists believe that gut microbiota play an important role in both the onset and progression of CRC, emerging evidence points to the significance […]
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