Circulating tumor DNA (ctDNA)—genetic material shed from tumors into the bloodstream—may help risk-stratify patients with Stage 3 colon cancer by tailoring chemotherapy options after surgery based on risk of cancer recurrence, according to new research […]
An international team of researchers has uncovered a promising new avenue for treating colorectal cancer, the world’s third leading cause of cancer-related deaths. By analyzing patient-specific genetic data, scientists identified a protein system that could […]
We often hear the phrase, “You are what you eat.” But what if it also applied to your children—even before they’re born? Research from the Texas A&M University Health Science Center (Texas A&M Health) suggests […]
A review in Clinical Epigenetics synthesizes growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter sperm epigenetic marks (DNA methylation, histone retention, and small non-coding RNAs). […]
Pulmonary fibrosis is a deadly disease in which the lungs become thickened and scarred, gradually losing their ability to deliver oxygen to the body. Now, scientists at UC San Francisco have identified a key cellular […]
Wiring up the brain’s trillions of circuit connections is an enormous job performed by a huge crew of molecules. Among the less understood members are circular RNAs, transcripts from DNA that assume a closed loop […]
A research team from the Medical University of Vienna and the Medical University of Graz has discovered a previously unknown genetic cause of hereditary optic atrophy, a degenerative disease of the optic nerve associated with […]
Researchers in Göttingen, Germany, have elucidated the structure and function of otoferlin, a protein that plays a crucial role in the hearing process. Loss of otoferlin or impairment of its function causes a frequent form […]
New research by UCLA Health has found a simple blood test could provide faster and more accurate diagnosis of ALS by measuring cell-free DNA. The noninvasive test could not only allow neurologists to rule out […]
Boston Children’s Hospital, along with Broad Clinical Labs and Roche Sequencing Solutions, has demonstrated that rapid genomic sequencing and interpretation are achievable in a matter of hours. This milestone not only sets a Guinness World […]
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