Discovery of C-reactive protein’s inflammatory pathway in diabetic kidneys offers new treatment avenues

A research team from the School of Chinese Medicine in the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has discovered that C-reactive protein (CRP) can exacerbate kidney inflammation caused by diabetes, also known as diabetic kidney disease (DKD), through a Smad3-NLRP3 inflammasome-dependent mechanism. Therefore, future research targeting CRP or the Smad3-NLRP3 mechanism may provide new treatment directions for DKD.

This article was originally published on MedicalXpress.com

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