The American College of Medical Genetics and Genomics (ACMG) has published a new clinical practice resource, “Management of Individuals with Heterozygous Germline Pathogenic Variants in RAD51C, RAD51D, and BRIP1: A clinical practice resource of the American College of Medical Genetics and Genomics (ACMG),” in its journal, Genetics in Medicine. The publication provides evidence-based guidance for clinicians managing individuals with heterozygous germline pathogenic variants (GPVs) in RAD51C, RAD51D, and BRIP1, genes associated with increased cancer risks, particularly ovarian and breast cancers.
This article was originally published on MedicalXpress.com
