Exploring placental malperfusion’s impact on fetal health and development in congenital heart disease

Researchers at Children’s Hospital of Philadelphia (CHOP) discovered that placental malperfusion (PMP), a condition that disrupts blood flow in the placenta, is common in fetuses with congenital heart disease (CHD) and is linked to poor fetal growth, longer hospital stays and potentially increased mortality. Published today in the Journal of the American College of Cardiology, the study, led by Rebecca Josowitz MD, Ph.D., also highlights that genetic changes in key pathways for placental and cardiac development may underlie PMP in CHD.

This article was originally published on MedicalXpress.com

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