Kidney damage that seemingly heals appears to mutate the DNA in the mitochondria of kidney cells, making the organ less resilient to future stressors and reducing its function over time, a study led by UT Southwestern Medical Center researchers shows. Their findings, published in Science, could lead to new treatments for acute kidney injury (AKI) and chronic kidney disease (CKD) and may explain some facets of aging in other organs and tissues throughout the body.
This article was originally published on MedicalXpress.com
