A research team, delving into the impact of excessive prenatal prednisone exposure (PPE) on fetal development, discovered that PPE leads to chondrodysplasia in female offspring and enhances their susceptibility to osteoarthritis (OA) in adulthood. The study also proposes that early targeting of PGC-1α could be a potential interventional strategy for PPE-induced OA susceptibility.
This article was originally published on MedicalXpress.com
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