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Ivermectin was touted as a cure for COVID, now it's being tested for cancer. But what can it actually treat?
Ivermectin was originally celebrated as a revolutionary treatment for parasitic disease in humans and animals. It has since evolved into... Read more -
Developing a human hepatocyte model with enhanced drug-metabolizing enzyme activity
A research team led by Associate Professor Shinpei Yamaguchi and the late Professor Masako Tada of the Faculty of Science,... Read more -
HIV can develop resistance to blockbuster antiviral lenacapavir—but at a cost to the virus
Long-acting antiviral medications are transforming HIV prevention and care, requiring only minimalistic dosing. But as the use of lenacapavir expands,... Read more -
Study compiles 30 years of adhesion GPCR modulators and their key concentrations
Adhesion GPCRs are a large class of surface proteins that recognize chemical and mechanical stimuli in the body. The rapidly... Read more -
Muscle repair may hinge on a timed metabolic 'switch,' study suggests
Scientists at the University of California, Irvine's School of Pharmacy & Pharmaceutical Sciences have discovered how muscle stem cells "flip... Read more -
Monthly cabotegravir-rilpivirine injections superior to standard oral ART for HIV with adherence challenges
Monthly injections of long-acting cabotegravir-rilpivirine are superior to standard oral antiretroviral therapy (ART) in persons with human immunodeficiency virus (HIV)... Read more -
A new drug target for sleeping sickness and Chagas? Why the PEX38 protein stands out
Researchers working with Professor Ralf Erdmann at Ruhr University Bochum, Germany, have discovered a critical vulnerability shared by the pathogens... Read more -
A blood marker could predict how people respond to antidepressants
Major depressive disorder (MDD) is among the most common psychiatric disorders, affecting approximately 330 people worldwide. This disorder is characterized... Read more -
Understanding GLP-1 signaling: A path to better therapies
About one in eight U.S. adults are currently taking a GLP-1 drug such as Ozempic, Wegovy, or Zepbound to treat... Read more -
Q&A: Prescription drug ads are everywhere. Is the 'ask your doctor' era over?
It's rare to make it through an episode of your favorite show without seeing a commercial for a prescription drug... Read more -
Patients with atrial fibrillation face higher bleeding risks when treated with 2 common medications
Patients with atrial fibrillation who are prescribed diltiazem to control heart rate alongside anticoagulants (blood thinners) such as apixaban or... Read more -
Novel delivery method bypasses blood-brain barrier to treat ALS symptoms
A researcher at the University of Missouri has made a promising breakthrough in the quest to help people with amyotrophic... Read more -
Antibody developed to protect immune system cells in vitro from a dangerous hospital-acquired bacterium
A monoclonal antibody created by the Nanobiotechnology for Diagnostics group (Nb4D) at the Institute of Advanced Chemistry of Catalonia (IQAC),... Read more -
FDA approves Dupixent for allergic fungal rhinosinusitis
The U.S. Food and Drug Administration has approved Dupixent (dupilumab) for the treatment of adult and pediatric patients aged 6... Read more -
Oral semaglutide found to lower risk of heart failure events in people with type 2 diabetes
An international clinical trial has found that an oral form of semaglutide, a widely used diabetes drug, reduced the risk... Read more
