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Most Alzheimer's cases linked to variants in a single gene
Potentially more than 90% of Alzheimer's disease cases would not occur without the contribution of a single gene (APOE), according... Read more -
Genetic study uncovers unknown causes of blindness
Researchers from Radboud University Medical Center and University of Basel have discovered new genetic causes of inherited blindness. Their study,... Read more -
Shared genes may influence both artery calcification and bone density
A new study published suggests that the connection between coronary artery calcification—a measure of calcium buildup in the arteries—and bone... Read more -
Disaster-related prenatal maternal stress has epigenetic outcomes
Maternal prenatal stress related to natural and human-made disasters can lead to epigenetic modifications in offspring, according to a recent... Read more -
Mapping proteins in African genomes reveals new paths to fight type 2 diabetes
Researchers have conducted the most comprehensive analysis to date linking plasma proteins to genetic variation in individuals from continental Africa.... Read more -
Childhood deafness: Researchers identify over 200 mutations, including previously unknown variants
Deafness, the most common sensorineural hearing loss at all stages of life, occurs either independently or as part of syndromes... Read more -
Shroom3 mutation linked to kidney scarring offers new drug target
Nearly 1 in 7 adults in the United States lives with chronic kidney disease, a condition that often advances quietly... Read more -
Targeting epigenetic modifiers and splicing regulators together may offer new acute myeloid leukemia treatment paths
Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic... Read more -
Schizophrenia-linked genetic variant renders brain receptor unresponsive to both natural and therapeutic compounds
A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence... Read more -
Brazil's genetic treasure trove: Supercentenarians reveal secrets of extreme human longevity
A Viewpoint published in Genomic Psychiatry by Dr. Mayana Zatz and colleagues at the Human Genome and Stem Cell Research... Read more -
Schizophrenia and osteoporosis share 195 genetic loci, highlighting unexpected biological bridges between brain and bone
A comprehensive genetic investigation led by Dr. Feng Liu at Tianjin Medical University General Hospital has uncovered striking molecular connections... Read more -
Proximity matters: Claudin-1 as an unexpected guardian of central tolerance
Scientists from the Institute of Molecular Genetics of the Czech Academy of Sciences, in collaboration with the Faculty of Science... Read more -
For the first time, a mechanism enabling breast cancer to metastasize to the brain has been deciphered
A large-scale international study, led by researchers from the Gray Faculty of Medical and Health Sciences at Tel Aviv University,... Read more -
Enzyme replacement therapy offers hope for ultra-rare Hunter syndrome
Ongoing clinical research at UNC could lead to a first-of-its-kind enzyme replacement therapy for Hunter syndrome, an ultra-rare disorder that... Read more -
Retrotransposon drives cancer by altering 3D genome structure
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer... Read more
