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'Master control switch' protein that heightens neurodegenerative disease offers new treatment target
UT Southwestern Medical Center scientists have identified a protein that appears to act as a master control switch for reactive... Read more
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Unlocking the genetics of blindness: New hope for sufferers of inherited retinal diseases
Researchers at the University of Oklahoma are advancing the fight against inherited retinal diseases (IRDs) with new genetic research that... Read more
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HIV's hidden persistence: How small changes affect replication speed and reactivation
University of Virginia School of Medicine scientists have uncovered a key reason why HIV remains so difficult to cure: Their... Read more
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Diagnosing Parkinson's using a blood-based genetic signature
Parkinson's disease is best known for its effects on the central nervous system. In addition, recent scientific advances generally emphasize... Read more
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Research untangles role of stress granules in neurodegenerative disease
Scientists from St. Jude Children's Research Hospital and Washington University in St. Louis report mechanistic insights into the role of... Read more
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Q&A: How cryptic mitochondrial DNA mutations reveal a hidden layer of the aging process
New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with... Read more
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Study reveals novel strategy for in vivo blood stem cell gene therapy
A team of scientists from the San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget) in Milan, Italy, has identified a unique... Read more
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Humans are seasonal creatures, according to our circadian rhythms
It's tempting to think that, with our fancy electric lights and indoor bedrooms, humanity has evolved beyond the natural influence... Read more
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Integrating pharmacogenomic guided prescribing into routine clinical practice
Pharmacogenomics studies how individuals respond to drugs based on their genetic code. Using that knowledge to guide prescribing in routine... Read more
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Gene expression after asbestos exposure may explain development of malignant mesothelioma
Gene expression leading to alterations in the DNA caused by asbestos exposure may explain the development of malignant pleural mesothelioma... Read more
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Gene editing disrupts Huntington's mutation in mice
Broad Institute researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and Friedreich's... Read more
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Fetal brain wiring sets up life-long sex differences in gene activity, study shows
A large international study led by scientists at FIMM, University of Helsinki, shows that many of the molecular differences between... Read more
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Silent X chromosome awakens with age: New explanation for sex differences in age-related diseases
Women age differently from men when it comes to health—particularly in conditions like cardiovascular disease and neurodegenerative disorders such as... Read more
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Boys who are overweight in their early teens risk passing on harmful epigenetic traits to future children
A new study suggests that boys who become overweight in their early teens risk damaging the genes of their future... Read more
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Wilms tumors: How genes and imprinting pave the way for cancer
A research team at the University of Würzburg has gained new insights into the development of kidney tumors in young... Read more