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AI-generated genomes could accelerate precision medicine without compromising patient confidentiality
A new AI system that creates simulated cancer genomes could reshape the tools used to analyze tumors, helping bring about... Read more
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Comorbidities in HIV: Big data study reveals molecular links
Why do people infected with the human immunodeficiency virus (HIV) often suffer from cardiovascular, liver, and other comorbidities? Researchers at... Read more
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Computational approach meets biology to connect neural progenitor cells with human disorders
For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has... Read more
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AI model simultaneously detects multiple genetic colorectal cancer markers in tissue samples
A multicenter study has analyzed nearly 2,000 digitized tissue slides from colon cancer patients across seven independent cohorts in Europe... Read more
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Why do some people age faster than others? Study identifies genes at play
It's a fact of life: Some people age better than others. Some ease into their 90s with mind and body... Read more
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Epigenomic landscapes of fat tissue cells reveal how they shape obesity risk
A new study has created the first single-cell map of how DNA is regulated and organized inside different cell-types of... Read more
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AI platform uses 3D visualization to reveal disease biomarkers in multiomics data
Researchers say the ability to visualize health data in three dimensions can unlock patterns and relationships among predictive biomarkers that... Read more
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How mutations in bodily tissues affect aging
Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over... Read more
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Epigenetic noise: Unappreciated process helps cells change identity
All cells in the body contain the same DNA, but different cell types express different genes; skin cells express genes... Read more
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Surprising gene activity shields certain nerve cells from ALS damage
By analyzing millions of messenger RNA molecules (mRNA) during the course of ALS, researchers at Stockholm University, in collaboration with... Read more
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Timing is everything: New method predicts key periods of gene activity in the developing brain
A Yale research team has created a new computer tool that can pinpoint when exactly genes turn on and off... Read more
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Q&A: How organoids could make gene therapy trials safer by identifying hidden risks early on
Ryuji Morizane, MD, Ph.D., of the Department of Medicine at Massachusetts General Hospital, is the senior/corresponding author of a new... Read more
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DNA repair enzyme Polβ shields developing brain from harmful mutations, study reveals
A research group led by the University of Osaka has discovered that the DNA repair enzyme Polβ plays a crucial... Read more
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Doctors seek best way to treat newly discovered genetic disorder
Most folks probably think of gene mutations as something people are born with, but genes can also change later in... Read more
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Scientists discover eight new schizophrenia genes
Researchers have discovered eight new genes associated with schizophrenia, in the largest exome-sequencing study of the disorder ever conducted. The... Read more