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Genetics

Genetics

US self-reported race and ethnicity are poor proxies of genetic ancestry, research suggests

June 5, 2025 Medical Xpress.com

Genetic ancestry is much more complicated than how people report their race and ethnicity. New research, using data from the National Institutes of Health’s (NIH) “All of Us” Research Program, finds that people who identify […]

Genetics

Novel truncated RNAs from jumping DNA encode reverse transcriptases in aging human brain

June 4, 2025 Medical Xpress.com

Alzheimer’s disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older. The disease has proven difficult to develop new treatments for, and available treatment options […]

Genetics

How our bones are repaired by skeletal stem cells: Scientist discover four major subtypes

June 4, 2025 Medical Xpress.com

Whether you are a competitive athlete or an older adult, strong bones are essential—not only for movement, but also for overall health. Now, a new study has shed new light on how our bones are […]

Genetics

Generative AI fills in the gaps in microscopy data to further genetic medicine

June 4, 2025 Medical Xpress.com

Skoltech researchers have enlisted generative artificial intelligence to complete the missing data on the distances between pairs of genes in DNA. This enables figuring out the 3D architecture of DNA molecules, which is in turn […]

Genetics

Faulty RNA ‘tails’ may drive neuron failure in ALS, study suggests

June 4, 2025 Medical Xpress.com

UC Irvine researchers conducted a study to better understand the molecular basis of amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder in which patients lose the ability to move, becoming weak and wheelchair bound before dying […]

Genetics

Determining the cause of cryopreservation fertility failures

June 4, 2025 Medical Xpress.com

According to the American Cancer Society, survivors of childhood cancer can face health problems later in their adult life. Many boys who undergo cancer treatment before puberty can lose the ability to produce sperm as […]

Genetics

Unlocking the Naᵥ1.9 channel: A hidden switch in pain and itch disorders

June 3, 2025 Medical Xpress.com

Imagine not feeling any pain when you stub your toe—or, conversely, experiencing constant burning pain or itching without an obvious cause. For some people, this is reality, caused by mutations in a single protein: the […]

Genetics

Brain study identifies microRNAs that likely contribute to psychiatric and neurodegenerative disorders

June 3, 2025 Medical Xpress.com

A study in Nature Aging from researchers at the UC Davis School of Medicine has identified specific microRNAs—non-coding RNAs that regulate gene expression within cells—that likely contribute to bipolar disorder, depression, schizophrenia, post-traumatic stress disorder […]

Genetics

DNA regions and key genes that activate liver regeneration identified

June 3, 2025 Medical Xpress.com

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury or partial resection. A study led by researchers at the University of Barcelona has identified the DNA […]

Genetics

CRISPR gene editing in blood stem cells linked to premature aging effects: Study offers solutions

June 3, 2025 Medical Xpress.com

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising […]

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