Cancer

Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic development and can positively (and less frequently, negatively) regulate gene expression. While progress has […]

Patients with leptomeningeal metastasis (LM) have historically had few treatment options. Now, researchers from The University of Texas MD Anderson Cancer Center have found a combination of targeted therapies, tucatinib and trastuzumab, plus the chemotherapy […]

A new editorial published in JAMA Oncology warns that cancer care progress is under threat from a trifecta of challenges: proposed federal budget cuts, a surge in medical misinformation, and a critical gap in public […]

When someone is diagnosed with colorectal cancer—which includes both colon and rectal cancers—many people immediately think “surgery.” And it’s true that surgery plays a central role in treatment for most patients. But whether it comes […]

New research shows first population-level evidence globally that a national HPV vaccination program can be highly effective in a high HIV-prevalence setting. In South Africa, where the burden of HIV remains high, women living with […]

Obesity increases the body’s need for insulin, forcing cells in the pancreas known as beta cells to ramp up insulin production to maintain blood sugar levels. Scientists have thought that this excessive insulin secretion is […]

Two new studies from investigators at Mass General Brigham challenge a decades-old assumption that the thymus, an organ best known for its role in establishing immune function in childhood, becomes irrelevant in adulthood. Using artificial […]

Researchers have discovered an antioxidant, glutathione, that cancer cells appear to be “addicted to” as fuel, opening new pathways for investigation and a potential drug that can restrict the way tumors use this nutrient.This article […]

For years, one of the most powerful weapons against certain blood cancers, called CAR-T cell therapy, has required an elaborate process: Doctors extract a patient’s immune cells, ship them to a specialized facility where they’re […]