Cancer

Cellular changes that appear during melanoma and lead to treatment resistance can be reversed with drugs—potentially opening the door to new or more effective treatments for the deadly disease, according to new Cornell research.This article […]

Lung adenocarcinoma (LUAD) is the most common form of lung cancer, accounting for nearly half of cases. Many patients are diagnosed at advanced stages, and five-year survival remains below 20%.This article was originally published on […]

About 50% of menopausal women experience genitourinary syndrome of menopause (GSM) that involves changes to the genitals, including the vagina, urethra and bladder. When estrogen levels drop during menopause, it can cause the GSM symptoms […]

Elironrasib led to meaningful and durable responses in patients with metastatic KRAS G12C-mutated non-small cell lung cancer (NSCLC), including after prior treatment with KRAS G12C inhibitors and in the presence of features linked to KRAS […]

Zenocutuzumab (Bizengri), a bispecific antibody that targets human epidermal growth factor receptor 2 (HER2) and HER3, led to responses in more than a third of patients with neuregulin 1 (NRG1)-positive cholangiocarcinoma, according to results from […]

Zocilurtatug pelitecan (zoci), also known as ZL-1310, an investigational antibody-drug conjugate (ADC) that targets the protein DLL3, demonstrated both safety and capacity to induce anticancer responses in patients with extensive-stage small cell lung cancer (ES-SCLC) […]

FX-909, a first-in-class investigational oral small molecule inhibitor of peroxisome proliferator-activated receptor gamma (PPARG), showed early signs of clinical benefit in patients with advanced urothelial carcinoma, according to results from a phase I clinical trial […]

A University of Alberta research team is shedding much-needed light on cancer cachexia, a severe muscle-wasting syndrome linked to up to a third of cancer deaths.This article was originally published on MedicalXpress.com

Triple-negative breast cancer is one of the most aggressive cancers. The name tells the story: It lacks the three main targets that make other types of breast cancers more treatable with powerful therapies.This article was […]

About 1 in 8 women in the U.S. will have breast cancer in their lifetime, making it the most common cancer among women. So you might wonder: Is there anything you can do to prevent […]