Cancer

In a prospective validation study, researchers at The University of Texas MD Anderson Cancer Center have demonstrated that a new mathematical model called LFSPRO was effective in supporting genetic counselor decision-making and more accurately predicted […]

Researchers and clinicians from National Taiwan University (NTU) and NTU Hospital have compiled the first large-scale genetic database for colorectal cancer (CRC) in Taiwan. This initiative identified inherited genetic abnormalities specifically linked to familial and […]

A new study from Karolinska Institutet shows that gene analysis of breast cancer tumors can identify patients who do not benefit from chemotherapy given before surgery. The findings, published in the journal Nature Communications, could […]

Cells manufacture proteins by following instructions encoded in messenger RNA, which is read in three-letter groups called codons. To translate this message, the cell uses molecules called transfer RNAs (tRNA). These act as intermediaries: they […]

Researchers at the University of British Columbia Faculty of Medicine have developed a new targeted cancer therapy that can precisely seek out and destroy tumor cells—showing strong results in preclinical studies that bring the breakthrough […]

Before her cancer diagnosis in early 2017, 48-year-old Caitlin Delaney, who is based in Australia, had been struggling with a troubling mix of symptoms comprising extreme fatigue, chronic sinusitis, and appetite changes including a sudden […]

A KAIST research team has identified the real reason why anticancer drugs kill cancer cells—targeted anticancer therapies do not simply block cancer proteins but rather shut down the “protein factories” inside the cells, forcing them […]

It may be possible to identify which pre-cancerous cells will develop into a rare type of blood cancer, due to new research showing that a single genetic change drives myeloid leukemia in children with Down […]

Scientists at Memorial Sloan Kettering Cancer Center (MSK) and their colleagues are shedding new light on a tumor’s earliest moments—revealing how lung cells with cancer-causing mutations recruit accomplices from healthy surrounding tissue to pave the […]

Efforts to develop effective therapies for MYC-amplified Group 3 medulloblastoma (G3-MB) are hindered by an incomplete understanding of how MYC expression is controlled in these tumors. MYC, an oncogene, has long been considered “undruggable,” because […]