Arthritis & Rheumatism

NDORMS researchers have identified a primary source of inflammatory IL-17 driving spondyloarthritis, paving the way for the development of targeted therapies to treat the condition.This article was originally published on MedicalXpress.com

In a first-of-its-kind genome-wide association study (GWAS) researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent. This crystalline arthritis is caused by […]

Patients with systemic sclerosis or Sjögren’s syndrome suffer from various inflammatory reactions triggered by the body’s own immune system. A team of researchers has investigated the role of certain immune cells in the pathogenesis of […]

The prevalence and severity of rheumatic adverse reactions in cancer immunotherapy is significantly underestimated, due to the lack of standardized screening protocols for malignancies in patients with autoimmune disorders. In response to the need for […]

Bone-destructive diseases such as osteoporosis and chronic inflammatory arthritis affect millions of people worldwide, causing pain, fractures, and decreased quality of life. These conditions often result from the dysregulation of osteoclasts—specialized cells responsible for breaking […]

Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has been identified in more than 110 countries around the world. The virus typically causes flu-like symptoms, but it can also trigger chronic, severe joint pain in […]

Some patients with lupus who possess specific antibodies are at a higher risk of thrombotic events such as a blood clot, stroke or heart attack, a new study led by Johns Hopkins Medicine researchers shows. […]

Mild structural changes visible in knee MRI scans are already common among adults in their thirties—even in those without knee pain or other symptoms. A study by the University of Oulu found signs of joint […]

Artificial intelligence (AI) is shaping the future of health care, offering new tools for earlier diagnosis of disease and more precise tracking of treatment outcomes. In a new Yale-led study, published in Arthritis Research & […]

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of “good” microbes in the gut is linked […]