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Alzheimer’s Disease & Dementia

Alzheimer's Disease & Dementia

Alzheimer’s disease can be reversed in animal models to achieve full neurological recovery

December 24, 2025 Medical Xpress.com

For over a century, Alzheimer’s disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery. Despite billions of dollars spent on decades of research, there has never […]

Alzheimer's Disease & Dementia

New ALS drug stabilizes decline with a trend toward improved strength and mobility for some

December 23, 2025 Medical Xpress.com

Historically, people with amyotrophic lateral sclerosis (ALS) experience a relentless decline in neurological function that eventually robs them of the ability to move, speak, eat or breathe. Now, researchers from Washington University School of Medicine […]

Alzheimer's Disease & Dementia

Modified tau thwarts aggregation in neurodegenerative disease—while retaining its biological function

December 23, 2025 Medical Xpress.com

A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its biological function while resisting aggregation, a pathological trait linked to neurodegenerative diseases called tauopathies.This article […]

Alzheimer's Disease & Dementia

Brain’s ‘pulse generators’ grow and shrink as memories are formed, study finds

December 23, 2025 Medical Xpress.com

Memories and learning processes are based on changes in the brain’s neuronal connections, and as a result, in signal transmission between neurons.This article was originally published on MedicalXpress.com

Alzheimer's Disease & Dementia

Menopause hormone therapy does not appear to impact dementia risk

December 22, 2025 Medical Xpress.com

A major review of prior research has found no evidence that menopause hormone therapy either increases or decreases dementia risk in postmenopausal women, in a new study led by University College London (UCL) researchers.This article […]

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Alzheimer's Disease & Dementia

Small study finds microdoses of cannabis stalled cognitive decline in Alzheimer’s patients

December 18, 2025 Medical Xpress.com

As the world’s population ages, the number of people living with dementias such as Alzheimer’s disease increases. Given the lack of curative treatments and the limited effectiveness of available medications, interest in new therapeutic approaches […]

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Alzheimer's Disease & Dementia

NU-9 halts Alzheimer’s disease in animal model before symptoms begin

December 18, 2025 Medical Xpress.com

An experimental drug developed at Northwestern University has demonstrated further promise as an early intervention for Alzheimer’s disease.This article was originally published on MedicalXpress.com

Alzheimer's Disease & Dementia

Alzheimer’s disease more prevalent in older people than previously thought

December 17, 2025 Medical Xpress.com

New research, published in Nature, has provided the first ever population-based data on the frequency of Alzheimer’s disease neuropathological changes (ADNC)—a key causal factor behind the development of dementia—and found that it is more prevalent […]

Alzheimer's Disease & Dementia

How an antiviral defense mechanism may lead to Alzheimer’s disease

December 17, 2025 Medical Xpress.com

One of the main proteins that contributes to Alzheimer’s disease is called phospho-tau (p-tau). When p-tau gets too many phosphate groups attached to it (a process called hyperphosphorylation), it starts to stick together and form […]

Alzheimer's Disease & Dementia

Concurrent frailty and depression likely boost dementia risk in older people

December 16, 2025 Medical Xpress.com

Concurrent physical frailty and depression likely boost the risk of dementia in older people, with the interaction of these two factors alone contributing around 17% of the overall risk, suggest the findings of a large […]

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