Alzheimer’s Disease & Dementia

Getting treatment within one week of a serious head injury can reduce the risk of developing Alzheimer’s disease by up to 41%, according to new research from Case Western Reserve University.This article was originally published […]

Lecanemab, sold under the name Leqembi, is a monoclonal antibody therapy for Alzheimer’s disease that clears toxic amyloid plaques and delays cognitive decline. Researchers from VIB and KU Leuven have now demonstrated the mechanism behind […]

A pill version of semaglutide, the ingredient in Ozempic and Wegovy, did not slow the progress of Alzheimer’s disease, drugmaker Novo Nordisk announced on Nov. 24.This article was originally published on MedicalXpress.com

Researchers at Université Savoie Mont Blanc, Radboud University and the University of Oxford’s Wellcome Center for Integrative Neuroimaging, report that attenuation of the brain’s intrinsic anticorrelation between the default mode and dorsal attention networks serves […]

A Korean research team has identified the most effective OLED color capable of enhancing cognitive function in Alzheimer’s patients. The OLED platform developed for this study can precisely control color, brightness, flicker frequency and exposure […]

Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is one of the leading causes of dementia worldwide, and currently has no definitive cure. Although antibody-based therapies that target amyloid β (Aβ) have recently been developed, their […]

More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as “lipoid granules,” along with the buildup of amyloid‐beta (amyloid) plaques and tau protein tangles. These observations led to […]

Researchers at the Paul Scherrer Institute PSI have clarified how spermine—a small molecule that regulates many processes in the body’s cells—can guard against diseases such as Alzheimer’s and Parkinson’s: It renders certain proteins harmless by […]

Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer’s disease and preserves cognitive function. The mechanism involves recruiting brain cells […]

Jijing Wang, Ph.D., and Hyun-Sik Yang, MD, of the Department of Neurology at Mass General Brigham, are the lead and senior authors of a paper published in Molecular Neurodegeneration titled “Plasma TDP-43 is a potential […]