Prediabetes may leave a lasting molecular “footprint” on adipose (fat) tissue which appears to make maintaining weight loss after bariatric surgery more difficult, according to new research being presented at the European Congress on Obesity […]
Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science Tokyo. They analyzed mouse embryonic forelimb cells […]
The COVID-19 lockdowns were difficult for everyone. Many people were stuck at home all day every day dealing with their uncertainty for the future, and some found it hard to avoid frequent eating and snacking […]
Injecting nivolumab (Opdivo) directly into precancerous oral lesions led to a reduction in lesion size and allowed some patients to avoid surgery, according to research from a Phase I clinical trial presented at the American […]
As the body ages, cells naturally accumulate dozens of genetic mutations each year. New research from Boston Children’s Hospital, published in Cell, finds that the brain’s resident immune cells, microglia, amass mutations in specific cancer-driving […]
Researchers led by Henry Daniell of the School of Dental Medicine have shown that extracts from bioengineered chewing gum reduce the levels of three microbes known to be associated with head and neck squamous cell […]
A hormone procedure commonly offered to IVF patients globally as an “add-on” does not improve chances of falling pregnant, according to an international analysis led by the University of Sydney.This article was originally published on […]
A phase 1 study aiming to test tolerability of combination therapy with trastuzumab deruxtecan and olaparib in Human Epidermal Growth Factor Receptor 2 (HER2)-expressing malignancies—including ovarian and uterine cancers—found a tolerable dosing schedule with promising […]
For patients with advanced solid tumors harboring specific genetic alterations, the first-in-class synthetic lethal combination of WEE1 inhibitor zedoresertib plus PKMYT1 inhibitor lunresertib demonstrated promising antitumor activity and was generally well-tolerated, according to Phase I […]
Women have described being dismissed, disbelieved, and left in serious pain during a routine womb examination that affects tens of thousands every year. Users of parenting forum Mumsnet who underwent hysteroscopy procedures also shared concerns […]
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