Scientists at Memorial Sloan Kettering Cancer Center (MSK) and their colleagues are shedding new light on a tumor’s earliest moments—revealing how lung cells with cancer-causing mutations recruit accomplices from healthy surrounding tissue to pave the […]
Efforts to develop effective therapies for MYC-amplified Group 3 medulloblastoma (G3-MB) are hindered by an incomplete understanding of how MYC expression is controlled in these tumors. MYC, an oncogene, has long been considered “undruggable,” because […]
Endometriosis is a chronic inflammatory condition in which tissue similar to the lining of the uterus is also found outside the uterus. Symptoms include menstrual pain, chronic pelvic pain, pain during intercourse, and in some […]
Researchers from the University of Cape Town’s (UCT) Scientific Computing Research Unit (SCRU) have uncovered a critical molecular “switch” that drives the formation of cancer-associated antigens. The study, published in Nature Communications, details how the […]
Brazilian researchers have developed an electrochemical sensor that can detect pancreatic cancer in its early stages. The device identifies the biomarker molecule CA19-9, which is associated with the disease, at low concentrations in a patient’s […]
Metabolic tumor volume—a biomarker derived from PET imaging—can more accurately predict progression-free survival for large B-cell lymphoma patients than the widely used International Prognostic Index. By identifying patients who are more likely to have poor […]
An experimental drug targeting triple-negative breast cancer overwhelms cancer cells with toxic fats, according to new tests on human-derived tumors in mice. Triple-negative breast cancer lacks three common drug targets, making it one of the […]
Immune checkpoint inhibitors (ICIs) have transformed treatment for many types of cancer. In some patients, however, ICIs are associated with immune-related complications that can affect the kidneys. These complications sometimes require care teams to pause […]
Researchers from Drexel University’s College of Medicine have identified a critical metabolic vulnerability in breast cancer that has spread to the brain, offering a promising new therapeutic target for a disease with few effective treatment […]
During pregnancy, a mother’s body undergoes vast structural and functional changes. But what many might not know is that the after-effects of these changes can last long after giving birth—and can even result in the […]
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