A new study has created the first single-cell map of how DNA is regulated and organized inside different cell-types of human fat tissue. The research shows that many genetic risk factors for abdominal obesity reside in epigenomic regions of fat cells, offering clues about how body fat is genetically and epigenetically regulated and how it might be better controlled. The study, by co-first authors Zeyuan (Johnson) Chen and Sankha Subhra Das, is published in Nature Genetics.
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