Famous film helps reveal brain region biased towards drug cues in individuals with heroin use disorder

Mount Sinai researchers have found that a brain region that is implicated extensively in value-based decision-making and craving in people with heroin use disorder—known as the orbitofrontal cortex (OFC)—shows synchronized responses biased toward drug content, outcompeting other typical subjects of attention and motivation, in a group of individuals with heroin use disorder who watched “Trainspotting,” the Academy Award-nominated 1996 movie about people who use heroin in Scotland.

This article was originally published on MedicalXpress.com

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