How tau protein weakens the brain’s vascular defenses in Alzheimer’s disease

A harmful form of the tau protein, which builds up in Alzheimer’s disease and similar brain disorders, can directly damage blood vessels in the brain, according to a new study by researchers at the Lewis Katz School of Medicine at Temple University. It does this by changing how the cells lining the blood vessels produce energy, which leads to inflammation and makes the blood-brain barrier—the brain’s protective shield—weaker.

This article was originally published on MedicalXpress.com

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