‘Inceptor’ that regulates insulin homeostasis offers new approach for diabetes therapies

In 2021, a research team led by Prof. Heiko Lickert from Helmholtz Munich discovered the insulin-inhibitory receptor “Inceptor” and its role as a suppressor of the insulin signaling pathway. Now, the researchers have unlocked another, even more significant function of the receptor: it binds insulin and directs its breakdown within beta cells. This discovery could lead to new therapeutic approaches that not only strengthen beta cell function but also enable a causal treatment for diabetes.

This article was originally published on MedicalXpress.com

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