VEXAS syndrome is a rare, adult-onset, life-threatening autoinflammatory disease caused by a genetic mutation. The pathophysiology is still unknown, but new work presented at the 2024 congress of EULAR—The European Alliance of Associations for Rheumatology—aims to provide a molecular and phenotypic characterization of hematopoiesis in VEXAS patients, and to develop cellular and humanized mouse models by gene editing.
This article was originally published on MedicalXpress.com
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