Study explores toxicity reduction in combination of trastuzumab deruxtecan and olaparib in HER2-expressing malignancies

April 20, 2026 Medical Xpress.com

A phase 1 study aiming to test tolerability of combination therapy with trastuzumab deruxtecan and olaparib in Human Epidermal Growth Factor Receptor 2 (HER2)-expressing malignancies—including ovarian and uterine cancers—found a tolerable dosing schedule with promising activity, according to results reported by Dana-Farber Cancer Institute medical oncologist Dr. Elizabeth Lee at the AACR Annual Meeting 2026, held April 17–22, in San Diego, Calif.

This article was originally published on MedicalXpress.com

Transform Your Kitchen: Mastering Allergy-Safe Cooking Through Ingenious Ingredient Swaps

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By Daniel Zane Bryant, author of “Living with Food Allergies: A Complete Lifestyle Guide” (available on Amazon at https://www.amazon.com/dp/B0G2BcGB2K) Navigating food allergies might initially feel overwhelming, yet it presents an exciting opportunity to reimagine familiar […]

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August 2, 2023 Community Partners

Effective communication is the foundation of any strong, healthy relationship. This article will explore the key elements required to build better communication between partners. We’ll cover the importance of active listening, using empathy and understanding […]

Will a nutritional supplement help you run better?

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Whether you jog to keep fit or compete in marathons, the physically demanding sport of running can deplete the body of essential nutrients. During a race like a half-marathon, a runner’s metabolism — or ability […]

Machine learning predicts asthma risk in children with early-life atopic dermatitis

April 25, 2026 Medical Xpress.com

Machine learning models can predict the risk for developing moderate-to-severe persistent asthma and allergic rhinitis in children diagnosed with early-life atopic dermatitis, according to a [...]
Rotavirus cases in children are rising, but a highly effective vaccine has slashed hospitalizations

April 25, 2026 Medical Xpress.com

Rotavirus is a highly contagious virus that spreads easily and can make babies and young children very sick. This year, doctors have been seeing more [...]
Researchers complete 16-year analysis of pediatric substance use health care patterns

April 25, 2026 Medical Xpress.com

Over the past 16 years, pediatric substance use-related visits (SUVs) to PEDSnet institutions have been increasing across all care settings and have increased at a [...]

Study explores toxicity reduction in combination of trastuzumab deruxtecan and olaparib in HER2-expressing malignancies

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Researchers complete 16-year analysis of pediatric substance use health care patterns