Neuroscience rarely enjoys clean experiments. Most brain disorders are mosaics of risk genes, aging, lifestyle and chance that leave their origins obscured. Huntington’s disease (HD) is different. It begins with a single genetic expansion—a repeated stretch of DNA letters in the HTT gene—that is both measurable and decisive. If you inherit a sufficiently long repeat, you will develop the disease. That stark clarity makes HD scientifically invaluable.
This article was originally published on MedicalXpress.com
