A research team affiliated with UNIST has unveiled a novel approach to halt the progression of colorectal cancer by inducing irreversible cellular aging. Their findings demonstrate that suppressing a neural protein called NSMF can effectively stop cancer cell proliferation. Led by Professor Young Chan Chae of the Department of Biological Sciences, the team revealed that NSMF plays a crucial role in managing replication stress—an abnormal condition caused by rapid DNA duplication in cancer cells. Normally, this stress helps cancer evolve, but excessive stress can damage DNA and trigger cell death or senescence. The paper is published in the journal Nucleic Acids Research.
This article was originally published on MedicalXpress.com
