Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease caused by repetitive head impacts (RHI). However, individuals with similar RHI exposure have shown differing pathology, suggesting a role for genetic variation. While a common Transmembrane Protein106B (TMEM106B) risk variant has been associated with greater CTE severity, its mechanism has remained unclear until now.
This article was originally published on MedicalXpress.com
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