In people with type 1 diabetes (T1D), the immune system shuts down the body’s ability to make the hormone insulin, responsible for regulating blood sugar and providing cells with glucose to produce energy. As a result, they are dependent on external sources of the hormone for the rest of their lives. Predicting who will develop T1D remains difficult, as existing genetic risk scores are largely limited to individuals with well-known high-risk variants.
This article was originally published on MedicalXpress.com
