Fentanyl is a highly potent and fast-acting synthetic opioid used to treat severe pain and is available in several forms, including injections, nasal sprays and skin patches. The study, which is published in the British […]
Following a rapid increase in popularity of GLP-1 drugs for diabetes and weight loss, such as semaglutide and tirzepatide, approximately one in eight U.S. adults now take these medications, which also provide cardiovascular benefits. However, […]
Two new studies from investigators at Mass General Brigham challenge a decades-old assumption that the thymus, an organ best known for its role in establishing immune function in childhood, becomes irrelevant in adulthood. Using artificial […]
Researchers have discovered an antioxidant, glutathione, that cancer cells appear to be “addicted to” as fuel, opening new pathways for investigation and a potential drug that can restrict the way tumors use this nutrient.This article […]
For years, one of the most powerful weapons against certain blood cancers, called CAR-T cell therapy, has required an elaborate process: Doctors extract a patient’s immune cells, ship them to a specialized facility where they’re […]
Cancer-fighting T cells do not simply “run out of energy.” They are molecularly reprogrammed. For years, mitochondrial dysfunction has been recognized as a hallmark of exhausted T cells in tumors. Yet how metabolic stress translates […]
Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well to immunotherapy. […]
For decades, members of the Rural Health Research Center have been studying how childhood experiences impact long-term outcomes. Much of this research has examined the negative effects of adverse childhood experiences (ACEs) such as divorce, […]
Psychedelic-assisted therapy may be no more effective than traditional antidepressants when patients know what drugs they are actually taking, according to a first-of-its kind analysis that compared how well each type of drug worked for […]
A global team of experts has identified a promising new approach to prevent recurrence of bacterial vaginosis (BV), a condition that affects millions of women worldwide. In a Phase I randomized clinical trial of women […]
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