Treating disease at birth: How a brief spike in testosterone sets the trajectory for disease that appears decades later

Spinal and bulbar muscular atrophy (SBMA) is a rare inherited disease that causes progressive muscle weakness and wasting in men. Patients typically develop early symptoms such as hand tremors in their 30s, but diagnosis usually occurs around age 40 when muscle weakness becomes more evident. Because the disease is triggered by high levels of testosterone, only males are affected.

This article was originally published on MedicalXpress.com

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