Drugs that block enzymes called tyrosine kinases are among the most effective targeted therapies for cancer. However, they typically work for only 40% to 80% of the patients who would be expected to respond to them. In a new study, MIT researchers have figured out why those drugs don’t work in all cases: Many of these tumors have turned on a backup survival pathway that helps them keep growing when the targeted pathway is knocked out.
This article was originally published on MedicalXpress.com

