From bench to bedside—research in mice leads to answers for undiagnosed human neurodevelopmental conditions

Nearly 30 years ago, researchers began studying the gene Astn1, which encodes the cell adhesion protein astrotactin 1 in mice, and its role in brain development. During this time, they learned a great deal about the function of astrotactin 1 in neuronal migration and the developmental problems that emerge when the protein fails.

This article was originally published on MedicalXpress.com

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