Small molecule blocks key glioblastoma driver, raising hopes for new treatment

UVA Comprehensive Cancer Center scientists have identified a molecule that blocks the gene responsible for glioblastoma, raising hopes that the molecule could become a much-needed new treatment for the deadliest brain cancer. Researcher Hui Li, Ph.D., previously discovered the “oncogene” responsible for glioblastoma, a cancer for which there are no treatments that extend life for more than a few months. In his follow-up work, published in Science Translational Medicine, Li reports the identification of a small molecule that blocked the gene’s activity in both cell samples and lab mice. In mice, the molecule proved effective without unwanted or harmful side effects.

This article was originally published on MedicalXpress.com

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