Researchers at Moffitt Cancer Center have developed a new way to predict how cancer cells evolve by gaining and losing whole chromosomes, changes that help tumors grow, adapt and resist treatment. In a new study, scientists describe a computational approach called ALFA-K that uses longitudinal, single-cell data to reconstruct how cancer cells move through different chromosome states over time and identify which configurations are favored by evolution.
This article was originally published on MedicalXpress.com
