Multi-scale analysis reveals FGFR1 inhibition as effective strategy against cardiac fibrosis

Through a comprehensive approach combining transcriptomic profiling, histological analysis, and functional validation in organoid and animal models, a research team led by Associate Professor Yoshinori Yoshida and Assistant Professor Shunsuke Funakoshi has identified fibroblast growth factor receptor 1 (FGFR1) as a key therapeutic target for cardiac fibrosis in dilated cardiomyopathy (DCM).

This article was originally published on MedicalXpress.com

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