Lactate-driven protein modification weakens natural killer cell cancer defenses

A research team led by Prof. Wang Yi and Wei Haiming from the University of Science and Technology of China (USTC), in collaboration with Prof. Ding Chen’s team from Human Phenome Institute at Fudan University, has elucidated the role of lactate-induced lysine lactylation (Kla) in modulating natural killer (NK) cell anti-tumor responses within the tumor microenvironment (TME). The study was published in Nature Immunology on June 10.

This article was originally published on MedicalXpress.com

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