Shedding light on what determines how cells become what they are meant to be—nerves, bone, muscles, etc.—can also help researchers understand how diseases develop when these biological programs break down. Now, researchers at Case Western Reserve University have discovered a key synergistic role for two epigenetic markers—molecules that help tell genes to turn on and off—involved in programming cell fate. Importantly, turning off these two markers causes genes to over-activate, disrupting normal cell development.
This article was originally published on MedicalXpress.com