Key protein Gfi1 found to regulate exhausted T cells in cancer and infection

Killer immune cells destroy cancer cells and cells infected by virus. These CD8+ T cells are activated after detection of viral infection or growth of “non-self” tumor cells. However, in chronic viral infection and cancer, the killer cells often lapse into “exhausted” CD8+ T cells that no longer can stem disease.

This article was originally published on MedicalXpress.com

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