In a first-of-its-kind genome-wide association study (GWAS) researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent. This crystalline arthritis is caused by […]
Patients with systemic sclerosis or Sjögren’s syndrome suffer from various inflammatory reactions triggered by the body’s own immune system. A team of researchers has investigated the role of certain immune cells in the pathogenesis of […]
Researchers comparing two injections commonly used to relieve knee pain from osteoarthritis—corticosteroid and hyaluronic acid—found that corticosteroid injections were associated with higher progression of the disease. The research was published today in Radiology. Hyaluronic acid […]
The prevalence and severity of rheumatic adverse reactions in cancer immunotherapy is significantly underestimated, due to the lack of standardized screening protocols for malignancies in patients with autoimmune disorders. In response to the need for […]
Bone-destructive diseases such as osteoporosis and chronic inflammatory arthritis affect millions of people worldwide, causing pain, fractures, and decreased quality of life. These conditions often result from the dysregulation of osteoclasts—specialized cells responsible for breaking […]
Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has been identified in more than 110 countries around the world. The virus typically causes flu-like symptoms, but it can also trigger chronic, severe joint pain in […]
Some patients with lupus who possess specific antibodies are at a higher risk of thrombotic events such as a blood clot, stroke or heart attack, a new study led by Johns Hopkins Medicine researchers shows. […]
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