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Month: April 2025

Genetics

Investigational gene therapy gives children with rare immune disorder a new lease on life

April 30, 2025 Medical Xpress.com

An investigational gene therapy has successfully restored immune function in all nine children treated with the rare and life-threatening immune disorder called severe leukocyte adhesion deficiency-I, or LAD-I, in an international clinical trial co-led by […]

Diabetes

Diabetes medication may increase risk of perioperative ketoacidosis

April 30, 2025 Medical Xpress.com

Sodium-glucose cotransporter-2 inhibitors (SGLT2i), or gliflozins, are medications used in the treatment of type 2 diabetes mellitus (T2DM). They are designed to lower high blood glucose levels typical in T2DM, and work by inhibiting the […]

Diabetes

Many Medicaid enrollees have restricted access to SGLT2 inhibitors, GLP-1 receptor agonists

April 30, 2025 Medical Xpress.com

Many Medicaid enrollees with type 2 diabetes have restricted access to cardioprotective medications, including sodium-glucose cotransporter-2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP-1 RAs), according to a study published online April 22 in the […]

Alzheimer's Disease & Dementia

Biological age linked to dementia risk in large population study

April 30, 2025 Medical Xpress.com

People whose biological age is higher than their chronological age may be more likely to develop dementia than people whose biological age matches or is lower than their chronological age, according to a study published […]

Weight & Obesity

Bariatric surgery: Different benefits for people with an increased risk of diabetes

April 30, 2025 Medical Xpress.com

More than 2.5 billion adults worldwide are overweight or obese. Many develop type 2 diabetes (T2D) and other complications. Bariatric surgery is an effective treatment option for significantly reducing weight and reducing the risk of […]

Diabetes

Rising diabetes risk among inpatients with depression sparks call for integrated care

April 30, 2025 Medical Xpress.com

A new study published in Health Data Science by researchers at Peking University reveals a concerning rise in the prevalence of type 2 diabetes mellitus (T2DM) among depression inpatients in Beijing from 2005 to 2018. […]

Genetics

Clusterin expression marks aging in hematopoietic stem cells

April 30, 2025 Medical Xpress.com

In recent years, there has been a growing trend of an aging patient population and an increasing prevalence of age-associated diseases, underscoring the need for advancing research into the biological mechanisms of aging. Of particular […]

Alzheimer's Disease & Dementia

Live human brain tissue reveals how Alzheimer’s-linked protein damages connections

April 30, 2025 Medical Xpress.com

Scientists using living human brain tissue have shown for the first time how a toxic form of a protein linked to Alzheimer’s can stick to and damage the connections between brain cells.This article was originally […]

Addiction

Machine learning brings new insights to astrocytes’ role in heroin addiction and relapse

April 30, 2025 Medical Xpress.com

Object recognition software is used by law enforcement to help identify suspects, by self-driving cars to navigate roadways and by many consumers to unlock their cell phones or pay for their morning coffee.This article was […]

Genetics

Seasonal gene expression affects drug effectiveness and metabolism in primates, study shows

April 30, 2025 Medical Xpress.com

Nagoya University researchers in Japan have found that drug effectiveness, alcohol tolerance, and carbohydrate metabolism change with the seasons. Their findings are based on a comprehensive seasonal gene expression map, which investigated over 54,000 genes […]

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