A study has identified a key disruption in cholesterol transport to the brain in patients with Alzheimer’s disease. The findings suggest that the lipoproteins in the cerebrospinal fluid of patients with Alzheimer’s have a reduced ability to deliver cholesterol to neurons, and that this impairment may be linked to the presence of the APOE4 genetic variant, one of the main known risk factors for the disease.
This article was originally published on MedicalXpress.com
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