Research challenges 'sugar hypothesis' of diabetic cataract development

New findings from investigators at Brigham and Women’s Hospital, a founding member of the Mass General Brigham health care system, contradict previous notions about sugar’s role in the onset of diabetic cataracts. Using an animal model that more closely recapitulates type 2 diabetes in humans, the research team found early signs of damage in the eye before the onset of type 2 diabetes, suggesting that diabetic complications may start during the pre-diabetic state. Results are published in the Journal of Biomedical Science.

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