Following computational predictions, scientists demonstrate that cancer drug counters pulmonary fibrosis

An experimental cancer drug with a favorable safety profile shows promise as a treatment for Idiopathic Pulmonary Fibrosis (IPF), according to a study published on August 23, 2022, in the American Journal of Respiratory and Critical Care Medicine by Yale School of Medicine, Mount Sinai, and National Jewish researchers. The drug, saracatinib, works as well or better than current FDA-approved treatments for IPF at countering fibrosis in preclinical models, including human lung cells in culture and fibrotic lung slices obtained from IPF patients who received transplants.

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